2020年7月23日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就嗜线虫真菌（Duddingtonia flagrans）NCIMB 30336 作为所有食草动物饲料添加剂的安全性和有效性发表科学意见。
经过评估，专家小组认为该添加剂对环境是安全的，由于缺乏数据，无法得出关于目标物种和消费者安全性的结论。当以建议的3×104衣原体孢子/千克体重和天的施用量使用时，所施用的菌株减少了牧场上的寄生线虫数量，从而使食草动物受益。部分原文报道如下：
Following a request from the European Commission, the EFSA Panel on Additives and products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on the safety and efficacy of BioWorma? (Duddingtonia flagrans NCIMB 30336) when used as a zootechnical feed additive for all grazing animals. Duddingtonia flagrans belongs to a group of nematophagous fungi that physically entrap nematodes through an adhesive hyphal net. The additive contains the fungus in the form of chlamydospores and is intended to control pathogenic nematodes on pasture, with subsequent benefits for grazing animals. No conclusions could be drawn on the safety for the target species due to lack of data. ■■■■■ As it is not possible to exclude the presence of secondary metabolites (other than flagranones) produced during fermentation and their potential carry‐over into animal products, safety for the consumer could not be established. The Panel concluded that the additive is not irritant to skin and eyes but is irritant to the respiratory tract and a respiratory sensitiser. No conclusion could be drawn on its skin sensitisation potential. Since D. flagrans is a naturally inhabiting soil organism of world‐wide distribution, the Panel considered that use of an additive based on this organism does not pose a risk for the environment under the intended conditions of use. The strain under application reduced the number of parasitic nematodes on pasture to the benefit of grazing animals when used at the recommended application rate of 3 × 104 chlamydospores/kg bodyweight and day.
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日期：2020-07-24
