2025年2月27日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就谷氨酸棒杆菌KCCM 80387发酵生产的L-精氨酸（l-arginine）作为所有动物饲料添加剂的安全性和有效性发表科学意见。
经过评估，专家小组认为该添加剂对目标物种、消费者和环境是安全的。评估中的添加剂被认为是非反刍动物物种氨基酸L-精氨酸的有效来源。为了使补充的L-精氨酸对反刍动物和非反刍动物同样有效，需要防止其在瘤胃中降解。部分原文报道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-arginine produced with Corynebacterium glutamicum KCCM 80387 as a nutritional feed additive for all animal species (category: nutritional additive; functional group: amino acids, their salts and analogues; and category: sensory additives; functional group: flavouring compounds). The production strain C. glutamicum KCCM 80387 is a genetically modified strain and raises no safety concerns. The FEEDAP Panel concluded that the additive does not pose any safety concern with regard to the production strain. The use of l-arginine produced by fermentation with C. glutamicum KCCM 80387 in feed as nutritional additive or as flavouring compound is safe for the target species. The FEEDAP Panel has concerns on the use of l-arginine in water for drinking. The use of l-arginine produced by fermentation with C. glutamicum KCCM 80387 in animal nutrition is considered safe for the consumers and for the environment. As regards the safety for the user, l-arginine produced with C. glutamicum KCCM 80387 is not irritant to skin, and not a dermal sensitiser but is irritant to the eyes and respiratory tract. The additive l-arginine produced by fermentation with C. glutamicum KCCM 80387 is regarded as an efficacious source of the essential amino acid l-arginine for non-ruminant nutrition. For the supplemental l-arginine to be as efficacious in ruminants as in non-ruminant species, it requires protection against degradation in the rumen. l-Arginine is also considered efficacious when used as a flavouring compound in animal nutrition.
