2024年10月24日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就里氏木霉CBS 114044生产的内切-1,4-β-木聚糖酶（endo-1,4-β-xylanase）作为育肥猪、蛋鸡和小型家禽物种饲料添加剂的安全性和有效性发表科学意见。
经过评估，专家小组得出结论，在拟议的使用条件下，该添加剂对育肥猪、蛋鸡和小型家禽物种是安全的。该添加剂在20，000 BXU/kg全价饲料下对育肥猪有效，在12，000 BXU/kg全价饲料下对所有产蛋家禽有效，在8000 BXU/kg全价饲料下对除产蛋家禽之外的小型家禽有效。部分原文报道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a product containing endo-1,4-β-xylanase (ECONASE® XT) as a zootechnical feed additive (digestibility enhancer) for pigs for fattening, laying hens and minor poultry species. ECONASE® XT is available in two liquid and three solid forms and is produced with a genetically modified strain of Trichoderma reesei (CBS 114044). The FEEDAP Panel concluded that the genetic modification of the production strain does not raise any safety concerns, and viable cells of the production strain and its DNA were not detected in the final products. The Panel also concluded that ECONASE® XT is safe for pigs for fattening, laying hens and minor poultry species at the proposed conditions of use. The use of the additive raises no safety concerns for the consumers of products derived from animals fed with the additive or for the environment. The liquid and solid forms of ECONASE® XT are non-irritant to the skin, but only the liquid forms were confirmed as non-irritant to the eyes and not dermal sensitisers. The Panel could not conclude on the irritation potential to the eyes and the dermal sensitisation potential for the solid forms. Due to the proteinaceous nature of the active substance, the additive is considered to be a respiratory sensitiser. The additive has the potential to be efficacious in pigs for fattening at 20,000 BXU/kg complete feed, in all laying poultry species at 12,000 BXU/kg complete feed and in minor poultry species other than laying birds at 8000 BXU/kg complete feed.
