2024年3月8日,据欧盟食品安全局(EFSA)消息,应欧盟委员会要求,欧盟动物饲料添加剂和产品(FEEDAP)研究小组就法夫驹形氏酵母NCAIM (P) Y001485生产的伏马菌素酯酶(fumonisin esterase)作为所有猪种(仔猪、育肥猪、母猪和小型生长、繁殖猪种)饲料添加剂的安全性和有效性发表科学意见。
经过评估,专家小组认为该添加剂在建议的使用水平下对断奶和哺乳仔猪以及育肥猪是安全的,对所有未成年生长猪品种的全价饲料中的含量不超过60 U/kg。关于添加剂对母猪的安全性,目前还不能得出结论。当以60U/kg的最低推荐浓度使用时,该添加剂作为技术饲料添加剂可有效减少伏马菌素对饲料的污染。这一结论可以推广到所有生长猪和繁殖猪以及其他小型猪种。部分原文报道如下:
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of the additive based on fumonisin esterase (Free Yeast® F), produced with a genetically modified strain of Komagataella phaffii. The additive is categorised as a technological feed additive, for the reduction of the contamination of feed by mycotoxins and intended for use in all pigs species (piglets, pigs for fattening, sows and minor growing and reproductive porcine species). It was shown that the production strain and its recombinant genes are not present in the additive. The FEEDAP Panel concluded that the additive is safe for weaned and suckling piglets and pigs for fattening, and all minor growing porcine species up to 60 U/kg complete feed. No conclusions can be drawn on the safety of the additive in sows. The use of the additive in animal nutrition is of no concern for consumer safety. The additive is dust-free, and therefore, respiratory sensitisation/irritation is unlikely. The additive is non-irritant to the eyes and the skin. No conclusion could be made on skin sensitisation. The use of the additive as a feed additive is considered safe for the environment. The Panel concluded that the additive is efficacious as technological feed additive for the reduction of feed contamination by fumonisins, when used at the minimum recommended concentration of 60 U/kg. This conclusion can be extrapolated to all growing and reproductive pigs and other minor porcine species.