2023年6月23日，欧盟食品安全局就一种枯草杆菌蛋白酶（subtilisin）的安全性评价发布意见。
据了解，这种食品酶是由非转基因副地衣芽孢杆菌菌株LMG S-30155生产的，旨在用于油类生产、植物/微生物/动物蛋白的水解、酵母加工和调味制剂的生产。
经过评估，专家小组认为，由非转基因副地衣芽孢杆菌菌株LMG S-30155生产的食品酶枯草杆菌蛋白酶不能被认为是安全的。部分原文报道如下：
The food enzyme subtilisin (serine endopeptidase, EC 3.4.21.62) is produced with the non-genetically modified microorganism Bacillus paralicheniformis strain LMG S-30155 by ENMEX SA de CV, now part of Kerry Food Ingredients (Cork) Ltd. The food enzyme is intended to be used in oil production, hydrolysis of vegetable/microbial/animal proteins, yeast processing and production of flavouring preparations. The production strain of the food enzyme contains known antimicrobial resistance genes and genes involved in bacitracin biosynthesis. Consequently, it does not fulfil the requirements for the QPS approach to safety assessment. Bacitracin was detected in the food enzyme and the ■■■■■ The presence of bacitracin, a medically important antimicrobial, in the food enzyme represents a risk for the development of resistance in bacteria. Due to the presence of bacitracin, the Panel concluded that the food enzyme subtilisin produced with the non-genetically modified Bacillus paralicheniformis strain LMG S-30155 cannot be considered safe.
