2023年3月17日，欧盟食品安全局（EFSA）就审查二硫代氨基甲酸酯（dithiocarbamates）的现有最大残留水平发布意见。
根据欧盟委员会第396/2005号法规第12章，欧盟食品安全局审查了二硫代氨基甲酸酯的最大残留限量。根据对现有数据的评估，提出了MRL提案，并进行了消费者风险评估。监管框架要求的一些信息缺失，并发现可能对消费者造成慢性/急性风险。因此，消费者风险评估仅被认为是指示性的，EFSA提出的一些MRL建议仍需风险管理者进一步考虑，并且还应考虑降低消费者风险的措施。部分原文报道如下：
According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the group of pesticide active substances dithiocarbamates. To assess the occurrence of metiram, ziram, maneb and mancozeb residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Regulation (EU) No 1107/2009, the MRLs established by the Codex Alimentarius Commission (codex maximum residue limits; CXLs) as well as the European authorisations and the import tolerances reported by Member States and the UK (including the supporting residues data) for metiram and mancozeb. Propineb and thiram were not considered further in this assessment since it is expected that all uses for these compounds, including import tolerances, have been withdrawn after the lowering of all the MRLs to the limit of quantification (LOQ) following the EFSA MRLs reviews completed, respectively, in 2020 and 2021. When reviewing the MRLs for the common residue definition (determined and expressed as CS2), EFSA was requested to consider also the monitoring data from organic samples collected and made available by the EURLs, reflecting the sulfur naturally occurring in crops and not related to the uses of the dithiocarbamates. based on the assessment of the available data, MRL proposals were derived, and a consumer risk assessment was carried out. Some information required by the regulatory framework was missing and a possible chronic/acute risk to consumers was identified. Hence, the consumer risk assessment is considered indicative only, all MRL proposals derived by EFSA still require further consideration by risk managers and measures for reduction of the consumer exposure should also be considered.
