2023年4月21日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就一种内切-1,4-β-葡聚糖酶（endo-1,4-β-glucanase）作为所有育肥家禽、饲养用于产蛋/繁殖的家禽、观赏鸟类和小猪（断奶和哺乳）的安全性和有效性。
据了解，该添加剂是由桔绿木霉IMI 360748生产的。经过评估，专家小组认为在建议的使用条件下该添加剂对目标物种、消费者和环境是安全的。该小组认为，在500 CU/kg全价饲料的剂量下，该添加剂对所有育肥家禽、饲养用于产蛋/繁殖的家禽和观赏鸟类是有效的，在350 CU/kg全价饲料的剂量下，对小猪（断奶和哺乳）是有效的。部分原文报道如下：
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of the feed additive containing endo-1,4-β-glucanase produced by Trichoderma citrinoviride IMI 360748 (Hostazym® C). The product is authorised as a zootechnical additive (functional group: digestibility enhancers) for use in chickens for fattening, minor poultry species for fattening and weaned piglets. This scientific opinion concerns the request for the renewal of the authorisation for the use in those species/categories, and the extension of use to chickens reared for laying, turkeys reared for breeding, minor poultry species reared for laying or breeding, ornamental birds and suckling piglets. The applicant provided evidence that the additive currently in the market complies with the conditions of the authorisation. There is no new evidence that would lead the Panel to reconsider previous conclusions that the additive is safe for the target species, the consumers, and the environment under the authorised conditions of use. This conclusion also applies to the target species for which a request for an extension of use is made. The additive is considered not a skin corrosive or eye irritant, but it should be considered a skin sensitiser. The Panel cannot conclude on the potential of the additive to be a skin irritant. Due to the proteinaceous nature of the active substance, the additive is considered a respiratory sensitiser. The Panel considers that the additive has the potential to be efficacious at 500 CU/kg complete feed in all poultry for fattening, reared for laying or breeding, and ornamental birds, and at 350 CU/kg complete feed in piglets (weaned and suckling, for the period in which solid feed is given).
