2023年1月11日,据欧盟食品安全局(EFSA)消息,应欧盟委员会要求,欧盟动物饲料添加剂和产品(FEEDAP)研究小组就一种内切-1,3(4)-β-葡聚糖酶(endo-1,3(4)-beta-glucanase)作为育肥鸡和断奶仔猪饲料添加剂的安全性和有效性发表科学意见。
据了解,该添加剂中是由斐济曲霉CBS 589.94生产的。经过评估,专家小组认为在建议的使用条件下该添加剂对育肥鸡和断奶仔猪是安全的。该添加剂作为一种动物技术添加剂,在10 FBG/千克饲料的最低推荐水平下,对育肥鸡和断奶仔猪是有效的。部分原文报道如下:
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of endo-1,3(4)-beta-glucanase produced by Aspergillus fijiensis CBS 589.94 (RONOZYME® VP (CT/L)) as a zootechnical feed additive for chickens for fattening and weaned piglets. based on the no observed adverse effect level identified in a subchronic oral toxicity study in rats and the tolerance trials provided, the additive was considered safe for chickens for fattening and weaned piglets at the proposed conditions of use. The Panel also concluded that the use of the product as a feed additive does not rise concerns for consumers and the environment. Owing to the lack of data obtained with the final formulations, the Panel could not conclude on the potential of the additive to be irritant to skin and eyes or on its potential as a dermal sensitiser. Due to the proteinaceous nature of the active substance, the additive is considered a respiratory sensitiser. The Panel concluded that the additive is efficacious as a zootechnical additive in chickens for fattening and weaned piglets at the minimum recommended level of 10 FBG/kg feed.