2022年8月10日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就乳酸片球菌（Pediococcus acidilactici） CNCM I-4622作为所有动物饲料添加剂的安全性和有效性发表科学意见。
经过评估，专家小组认为在拟议的使用条件下，该添加剂对目标物种、消费者和环境是安全的。该添加剂在1×109 CFU/kg全价饲料中表现出降低液体饲料中pH值和大肠菌群生长的潜力。部分原文报道如下：
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Pediococcus acidilactici CNCM I-4622 when used as a technological additive (acidity regulator and hygiene condition enhancers) for all animal species. The product is intended for use in mash compound feeds and/or solid feed materials used for the preparation of liquid feeds at a minimum inclusion level of 1 × 109 CFU kg feed. The bacterial species is considered by EFSA to be eligible for the qualified presumption of safety (QPS) approach. As the identity of the strain has been clearly established and it did not show acquired resistance to antibiotics of human and veterinary importance, the use of this strain in animal nutrition is considered safe for the target species, consumers and the environment. The additive is considered to be a respiratory sensitiser but is not irritant to eyes/skin or a skin sensitiser. Pediococcus acidilactici CNCM I-4622 at 1 × 109 CFU/kg complete feed showed the potential to reduce the pH and the growth of coliforms in liquid feeds. Pediococcus acidilactici CNCM I-4622 is compatible with halofuginone, diclazuril, decoquinate and nicarbazin at the highest authorised levels for chickens for fattening.
